Aging and Immunology is a rapidly evolving field that examines how immune function changes across the lifespan and how these changes influence susceptibility to infections, vaccine responsiveness, chronic inflammation, and age-related diseases. As populations worldwide continue to age, understanding immune senescence and immune remodeling has become essential for designing effective preventive and therapeutic strategies. This session on Aging and Immunology brings together insights from immunology, gerontology, vaccinology, and public health to address the biological and clinical implications of immune aging.

One of the central challenges in aging populations is the gradual decline in immune responsiveness, which affects both innate and adaptive immune systems. Reduced vaccine efficacy, increased vulnerability to infectious diseases, and altered inflammatory responses are key concerns in older adults. These challenges are frequently discussed at leading Immunology Conferences, where researchers explore mechanisms of immune dysregulation, chronic low-grade inflammation, and impaired immune memory associated with aging. This session highlights current research aimed at improving immune resilience and restoring protective immunity in older populations.

The interaction between aging and immunology also has major implications for vaccine development and immunization strategies. Age-specific vaccine formulations, adjuvants, and dosing schedules are increasingly being explored to enhance immune responses in older adults. Closely linked to this work is the concept of immune aging research, which investigates biomarkers of immune decline, predictors of vaccine responsiveness, and interventions that may slow or reverse immunosenescence. These scientific advances are critical for improving disease prevention outcomes and reducing healthcare burdens associated with aging societies.

Beyond biological mechanisms, this session also considers the broader public health and healthcare system dimensions of immune aging. Factors such as comorbidities, nutrition, lifestyle, and access to preventive care significantly influence immune health in older adults. By integrating laboratory research with clinical and population-level studies, this session provides a comprehensive understanding of how aging shapes immune function and how immunological interventions can be optimized to support healthy longevity.

Participants engaging with this session will gain valuable perspectives on emerging immunological discoveries, translational research approaches, and policy considerations that inform vaccination and disease prevention strategies for aging populations. The knowledge shared contributes to advancing age-inclusive immunology practices and strengthening global preparedness for infectious disease threats affecting older adults.