One Health is an integrated approach that recognizes the interdependence of human, animal, and environmental health in shaping immune risk, disease emergence, and prevention strategies. Health outcomes are influenced by complex interactions across ecosystems, where pathogens circulate between species and environmental conditions alter exposure patterns. This session explores how immunology-informed One Health frameworks support coordinated prevention, surveillance, and response across sectors.

Interactions between humans, animals, and the environment create shared immune challenges that cannot be addressed in isolation. Zoonotic pathogens, antimicrobial resistance, and environmentally driven disease transmission highlight the need for cross-sector collaboration. These connections are frequently examined at leading Immunology Conferences, where experts emphasize how immune data from multiple domains improves understanding of transmission pathways and strengthens prevention strategies. This session highlights how integrated immunological insight enhances preparedness and risk reduction.

A central focus of this session is human–animal–environment health, which brings together veterinary science, public health, and environmental monitoring to identify immune threats early. Immune responses observed in animal populations can provide early warning of emerging pathogens, while environmental surveillance reveals exposure drivers that influence immune vulnerability. This session examines how shared data systems and coordinated research improve detection, response, and intervention planning.

One Health approaches also support sustainable prevention by addressing upstream drivers of disease. Land-use change, climate variability, and biodiversity loss alter host–pathogen interactions and immune pressures across species. The session addresses how immunology contributes to understanding these dynamics and informs policies that reduce long-term health risk. Ethical governance, data sharing, and capacity building across sectors are emphasized as essential components of effective One Health implementation.

Participants engaging with this session will gain insight into how immunology bridges disciplines to address complex health challenges. By integrating immune science with ecological and veterinary perspectives, this session provides a comprehensive view of how One Health strategies strengthen global health resilience and coordinated disease prevention.