One Health, Veterinary & Zoonotic Vaccines address the interconnected nature of human, animal, and environmental health by focusing on diseases that cross species boundaries. This session examines how vaccines developed for animals and humans contribute to preventing zoonotic spillover, controlling endemic diseases, and strengthening global health security. As human–animal interactions intensify due to urbanization, agriculture, and climate change, integrated vaccination strategies are increasingly essential.

Insights presented at Vaccine Conferences highlight that many emerging infectious diseases originate in animal reservoirs before adapting to human transmission. Vaccines targeting livestock, wildlife, and companion animals play a critical role in interrupting transmission chains at their source. Preventing disease spread within animal populations reduces pathogen circulation, mutation opportunities, and the risk of cross-species adaptation that can lead to outbreaks.

The One Health, Veterinary & Zoonotic Vaccines session explores how veterinary vaccinology supports both animal health and human disease prevention. Vaccines for zoonotic pathogens such as influenza viruses, coronaviruses, and bacterial agents are designed with consideration for species-specific immune systems and ecological contexts. These efforts require collaboration among veterinarians, immunologists, epidemiologists, and environmental scientists to ensure effective implementation.

Advances in zoonotic vaccine development have expanded the use of modern platforms across animal health applications. Recombinant vaccines, vector-based approaches, and novel adjuvants improve immune responses while supporting large-scale deployment in agricultural and wildlife settings. These innovations enhance disease control while minimizing economic losses and food security risks associated with animal disease outbreaks.

This session also addresses challenges unique to One Health vaccination, including surveillance integration, regulatory alignment, and vaccination coverage across diverse species. Coordinated monitoring systems are needed to track disease prevalence and vaccine impact in animal populations. Regulatory frameworks must balance safety, efficacy, and feasibility while supporting cross-sector collaboration.

Participants gain insight into how One Health vaccination strategies protect ecosystems, safeguard food systems, and reduce global disease burden. By integrating veterinary and human vaccine science, this session underscores the importance of holistic approaches in preventing zoonotic diseases and promoting sustainable health outcomes worldwide.